Towards the end of the 18th Century, that is about 1777, a man called Richard Jones, of Aberffraw some 15 miles away, enraged the churchmen of the village by listening to the preaching of an itinerant evangelist preacher, and by showing respect to the Word of God by doffing his hat. For this he was sorely persecuted and virtually driven from his home. It is said that he held his staff vertical and let is fall to the ground, deciding to travel away in whatever direction that his staff pointed. The staff, it is said, pointed in the direction of Holyhead, and thither he went, with is wife, family and chattles on a cart. When he arrived at Holyhead at nightfall, he did not get a very good reception, and could not find a place "to lay down his head". But it is said that "an old sinner" took pity on him and offered him an old house to rent.

It was there that the Methodist cause is said to have begun at Holyhead, and the people gathered at his home.

In 1808, the first chapel was built, being only 36 feet by 27 feet! It was extended in 1815, rebuild in 1847, and extended again in 1856. In 1886 the present chapel was built at a cost of £3,511-15-9! It seats nearly 1000 people. The chapel manse, now named "Yr Hendre" was built in 1925.